glutathione redox mechanism The cycle, demonstrating the inter-conversion of Figure 1 from Glutathione redox

In GBM, CA9 (carbonic anhydrase 9), a downstream target gene of hypoxia-inducible factor HIF-1, has been shown to increase radiation-induced ferroptosis when it is knocked down, leading to a significant increase in intracellular ROS levels and increasing tumor cell sensitivity to radiation-induced oxidative stress ( 4.3 Ferroptosis-targeting nanomaterials In recent years, the use of nanomaterials has provided new insights into the clinical translation of ferroptosis-targeted therapy for GBM

147 Lopez-JimenezF.Krell-RoeschJ.VassilakiM.MielkeM

The upper layer (plasma) was separated immediately after centrifugation

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